Titlebook: Biophysics of RNA-Protein Interactions; A Mechanistic View Chirlmin Joo,David Rueda Book 2019 Springer Science+Business Media, LLC, part of

山間窄路

云狀

純樸

Ana Paula Barbosa-Fohrmann,Marcelo Fabrin recent biophysical and single-molecule studies that have revealed important molecular bases and dynamic processes governing the biogenesis of microRNA with an?unprecedented high spatiotemporal resolution, thus, uncovering hidden steps and intermediate conformations that are difficult to obtain using conventional approaches.

Outmoded

Evolving Methods in Defining the Role of RNA in RNP Assemblymbination of single-molecule biophysical and ensemble methods that can dissect single protein–RNA interaction. The advantage of this approach is that it provides a potential tool to identify early-stage molecular defects that may contribute to the onset of neurodegenerative diseases.

Devastate

A Single-Molecule View on Cellular and Viral RNA Synthesisr its versatile mechanisms but also to develop new therapeutics against these devastating human pathogens. Here, we summarize the recent advances in cellular and viral RNA production using in vitro single-molecule techniques.

JOT

Single-Molecule Optical Tweezers Studies of Translationactions between ribosome and nascent polypeptide. In this chapter, we will give a brief introduction of the single-molecule optical tweezers technique and a comprehensive overview of its application in translation.

Analogy

Biophysical and Biochemical Approaches in the Analysis of Argonaute–MicroRNA Complexesiophysical studies have revealed the complexity in the interactions between miRNA and the effector protein Argonaute (Ago) as well as between Ago and the target mRNA. In this chapter, we present these findings that significantly enhanced our knowledge of the assembly and regulation by Ago–miRNA complexes.

寬容

granite

Latin American Foreign Policiess is significant but quite challenging. Recent advances and structural information about different RNA–protein complexes open the possibility of dissecting the interactions in the molecular level. This review is an overview of different types of RNA-binding proteins and how they recognize their target RNAs.

Notorious

Book 2019s how proteins and RNA interact to carry out biological functions such as protein synthesis, regulation of gene expression, genome defense, liquid phase separation and more..The topics addressed in this volume will appeal to researchers in biophysics, biochemistry and structural biology. The book is