Titlebook: Biomedical Translational Research; Drug Design and Disc R.C. Sobti,Naranjan S. Dhalla Book 2022 The Editor(s) (if applicable) and The Autho

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Polypharmacology: New Paradigms in Drug Development of drugs. The advent of various in silico computational approaches would help to identify multi-target activates and anticipate potential selectivity issues early in the iterative drug design process. This would not only prevent costly failures but also offer the possibility of identification of no

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Pedagogy

Genomic Approaches for Drug Repositioningrch. Drug repositioning (DR) is an alternative approach to usurp already available drugs or drug candidates with FDA approval, which have been initially developed for specific diseases and re-establish their use for other diseases. Modern genomic methods for drug repositioning involve the usage of c

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Awning

Precision Radiomolecular Oncology: Challenging the Classical Statistical Evidence-Based Medicineer cells, evolving from the “normal cells” of . are thus governed by the same rules. This is one of the reasons why, despite the advances in modern oncology, cure is not achievable in several cancers. Driven by the challenges posed by cancerous tissue, several new multipronged strategies have been e

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Drug Repositioning of the Phenylpiperazine Derivative Naftopidil in Prostate Cancer Treatmentin elderly men. In drug repositioning studies conducted from our laboratory, we demonstrated that naftopidil has growth inhibitory effects by inducing G. cell cycle arrest in cancer cells, fibroblasts, and vascular endothelial cells. Moreover, naftopidil has been shown to bind directly to and inhibi

Kinetic

Inclement

Nanotechnology in Dentistryefined dental practice to be able to efficiently and effectively achieve the goal of positive oral health. The nanomaterials’ enhanced mechanical properties, increased durability in the oral environment, biocompatibility, better aesthetics and, above all, atraumatic experience to the patients make t