Titlebook: Biomaterials as Stem Cell Niche; Krishnendu Roy Book 2010 Springer-Verlag Berlin Heidelberg 2010 Biomaterials.Cell Differentiation.Cell Si

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https://doi.org/10.1007/978-3-8349-6522-6even death. Vascular regeneration engineering holds the promise of permanent, effective treatments for many vascular diseases. However, many challenges also remain to bring the therapy to the clinic, as the formation of blood vessels is a complicated process. One major challenge facing vascular engi

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https://doi.org/10.1007/978-3-322-88627-9citing advances in neural stem/progenitor cell (NSPC) biology promise cellular based therapeutics. Major strategies seek to transplant exogenous NSPCs or recruit endogenous NSPCs in order to protect injured neurons or replace the function of lost neurons, but current methods are hindered by poor reg

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Macht, Konkurrenz und Demokratie,become activated as proliferating myogenic precursors, differentiate into myoblasts, and ultimately fuse into new, multinucleated myofibers. Unfortunately, this paradigm breaks down with aging and instead of becoming activated upon injury, satellite cells remain quiescent. Recent work, however, has

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Integration of Biomaterials into 3D Stem Cell Microenvironments,–cell contacts, soluble molecule signals and physical interactions with the ECM. In contrast to conventional 2D culture systems, barriers to diffusion within 3D cultures limit the effectiveness of media manipulation as a method to direct cell behavior. Efforts to engineer stem cell microenvironments

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Stem Cell Interaction with Topography,nces have shown that substrate topography, one of the biophysical properties of the microenvironment, can affect stem cell fate, such as the maintenance of embryonic stem cells and the differentiation of adult and embryonic stem cells. The underlying mechanism of how topography influences stem cells