Titlebook: Biomarkers of the Tumor Microenvironment; Basic Studies and Pr Lars A. Akslen,Randolph S. Watnick Book 20171st edition Springer Internation

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Cancer Immunity and Immune Evasion Mechanisms T cells are instrumental in eliminating cancer cells by secreting various cytokines and activating and recruiting other cell types such as macrophages and granulocytes. However, CD4+ T cell-mediated activation of CD8+ T cells and subsequent cytotoxic activity of the CD8+ T cells represent the major

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Immunology of Solid Tumors Beyond Tumor-Infiltrating Lymphocytes: The Role of Tertiary Lymphoid Struer, which focuses on breast cancer, describes currently available data on TILs as a prognostic biomarker, challenges on the assessment of TILs, and TLS and the efforts of the International Immuno-Oncology Biomarker Working Group on standardization of its assessment.

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