Titlebook: Biomarkers of the Tumor Microenvironment; Basic Studies and Pr Lars A. Akslen,Randolph S. Watnick Book 20171st edition Springer Internation

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Konstruktion für die Additive Fertigung 2020sions. Here, we critically evaluate several inflammatory parameters as biomarkers and prognostic tools for cancer. Colorectal cancer (CRC) represents a paradigm of the causative relationship between chronic inflammatory disease and cancer development. However, close examination reveals that for CRC,

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Problemorientierte Programmkonstruktion,e “band-aids of the blood,” these cells rapidly activate, aggregate, and release a potent milieu of growth factors, cytokines, and other biological mediators at the site of vascular damage, forming a clot. Compelling evidence has revealed that tumors can co-opt the normal functions of platelets in o

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Untersuchungsmethoden und Forschungsdesign,nic development. Over the past two decades, the expression, localization, regulation, and function of the NRP family have been intensely studied. The two-member family composed of neuropilin 1 (NRP1) and neuropilin 2 (NRP2) has now been shown to drive diverse processes including neuronal guidance, v

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Untersuchungsmethoden und Forschungsdesign, Recent insights into the epigenetic heterogeneity of cancer have emphasized a need to address the underlying mechanisms driving tumor cell plasticity. Epithelial-to-mesenchymal transition (EMT)-related transdifferentiation programs are prevalent in aggressive tumors displaying a drug-resistant, inv

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Als Kategorisierende in Erscheinung treten,-inclusive model that encompasses the complete picture of the different conditions and pathways operating in human tumors. Application of gene expression signatures is one way of mining the complex tumor landscape, and this has been proposed to represent a robust method to reflect the many signaling

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