Titlebook: Biomarkers of the Tumor Microenvironment; Lars A. Akslen,Randolph S. Watnick Textbook 2022Latest edition The Editor(s) (if applicable) and

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thyroid-hormone

Konstruktion elektrischer Maschinenof the blood,” platelets rapidly activate, aggregate, and release a plethora of growth factors, cytokines, and other biological mediators at sites of vascular damage, thereby forming a clot. Compelling evidence has revealed that tumors can co-opt the normal functions of platelets to advance disease

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https://doi.org/10.1007/978-3-662-12180-1 homeostasis and function. Although it is well known that both the vascular system and the immune system display strong influences on cancer, nerves have often been seen as more silent partners in the tumor microenvironment. However, studies from different tissue types have revealed similarities in

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Rene Bastian Lippert,Roland Lachmayerd NRP2 act as co-receptors for a multitude of stimulatory growth factors such as VEGF, PGF, HGF, and PDGF. Alternately, NRPs can bind to ligands of the SEMA3 family of chemorepulsive guidance cues. Consequently, these unique receptors can toggle between opposing pro-tumorigenic and anticancer roles.

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https://doi.org/10.1007/978-3-030-98950-7biomarker; morphology; tumor microenvironment; tumor-vascular interaction; cancer microenvironment; Predi

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978-3-030-98952-1The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl

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Lars A. Akslen,Randolph S. WatnickCovers basic model studies of novel biomarkers and treatment targets of the microenvironment.Explores a variety of different classes of biomarkers in human tumors.Features new chapters covering the us

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