Titlebook: Biomarkers of the Tumor Microenvironment; Lars A. Akslen,Randolph S. Watnick Textbook 2022Latest edition The Editor(s) (if applicable) and

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https://doi.org/10.1007/978-3-658-36125-9illance. As most other tissues, solid tumors have lymphatics, and inherent and draining lymphatics influence solid tumor development and progression. Tumor lymphatics are also associated with metastasis to regional lymph nodes and dissemination to distant organs. Recent insights indicate that the tu

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Epistemologie des Postfaktischen,as questioned the exclusive tumor-supportive function of the tumor stroma and suggested that the stroma might also act as a barrier to inhibit tumor metastasis. With consideration of this shift in dogma, we discuss the role of a specific part of the tumor stroma, the insoluble extracellular matrix (

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https://doi.org/10.1007/978-3-658-34597-6e stroma is comparable to the activated stroma at the site of wound healing. The crosstalk between malignant cells and the surrounding stromal fibroblasts, an essential part of the reactive stroma, is a continuous, reciprocal force that modulates cancer progression. This communication unfolds at sev

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https://doi.org/10.1007/978-3-476-99555-1hly infiltrated by a complex network of immune cells, which includes innate (macrophages, mast cells, neutrophils, dendritic cells, natural killer cells, innate lymphoid cells, and myeloid-derived suppressor cells) and adaptive T and B lymphocytes. This diverse set of cells, their interactions, and

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Arithmetik und spezielle Funktionen,re, we review several inflammatory parameters as biomarkers and prognostic tools for cancer. Colorectal cancer (CRC) represents the paradigm of a causative relationship between chronic inflammatory disease and cancer development. However, close examination of the data reveals that the risk of CRC in

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