Titlebook: Biomarkers in Breast Cancer; Giampietro Gasparini,Daniel F. Hayes Book 2006 Humana Press 2006 DNA.classification.gene expression.systemic

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Book 2006reast cancer patients. The authors cover both the major advances in sophisticated molecular methods and the state-of-the-art in conventional prognostic and predictive indicators. Among the topics discussed are the relevance of rigorous study design and guidelines for the validation studies of new bi

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, as a Prognostic and Predictive Indicatorpy. The aim of this chapter is to evaluate why one of the most promising and most intensively studied markers is not recommended for routine clinical use to date. The pitfalls of . analysis and the challenges of well-designed . studies are elucidated and the need of carefully planned studies using an optimal . analysis method is pointed out.

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