Titlebook: Biology, Computing, and the History of Molecular Sequencing; From Proteins to DNA Miguel García-Sancho Book 2012 Palgrave Macmillan, a divi

intricacy

From Chemical Degradation to Biological Replication (1962–1977)xwell, J.J. Thompson and Ernest Rutherford all producing important contributions to the structure of the atom and its electromagnetic properties (Warwick, 2003; Buchwald and Warwick, 2001; Hendry, 1984). From the early 1930s onwards, a group of Cavendish investigators were among the pioneers in the application of X-ray crystallography to proteins.

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A New Approach to Sequencing at Caltechhe histories of their home institutions. These personal and institutional differences framed the practices that Hood’s team introduced into sequencing, and differentiated his approach not only from Sanger’s, but also from other contemporary automation projects.

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Politisches Interesse und Bürger bewusstseinogy market — which in the mid-1980s was regarded by biologists as an unprecedented instance of cooperation between academia and industry (e.g. Kenney, 1986). However, the development of the chemical and pharmaceutical industries at the turn of the twentieth century constitutes a clear antecedent.

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Sequencing Software and the Shift in the Practice of Computationdge, computer programs were designed to assist in protein sequence determination during the 1960s and a considerable number of researchers in Sanger’s group continued working on proteins after their move to the LMB.

adipose-tissue

The Commercialisation of the DNA Sequencerogy market — which in the mid-1980s was regarded by biologists as an unprecedented instance of cooperation between academia and industry (e.g. Kenney, 1986). However, the development of the chemical and pharmaceutical industries at the turn of the twentieth century constitutes a clear antecedent.

Intersect

2946-9643 f this practice comprises not only academic biology, but also the world of computer-assisted information management. The book uncovers this history, qualifying the hype and expectations around genomics.978-1-137-54332-5978-0-230-37093-7Series ISSN 2946-9643 Series E-ISSN 2946-9651

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https://doi.org/10.1007/978-3-658-16889-6nd experimental strategies designed to replicate biological processes rather than chemically degrade molecules. Molecular biology also framed the gradual expansion of sequence determination from proteins to nucleic acids, through the study of the so-called coding problem — that is, how DNA, as the g

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Conclusions: A Long History of Practicesnd experimental strategies designed to replicate biological processes rather than chemically degrade molecules. Molecular biology also framed the gradual expansion of sequence determination from proteins to nucleic acids, through the study of the so-called coding problem — that is, how DNA, as the g