Titlebook: Biology and Management of Multiple Myeloma; James R. Berenson Book 2004 Springer Science+Business Media New York 2004 Staging.anemia.bone

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Immunological Approaches to Multiple Myeloma,Tumor cells express tumor-associated protein antigens on the cell surface, as well as peptides of the protein presented in the groove of the major histocompatibility complex (MHC). Although most tumor antigens are shared self-antigens, they can be regarded as tumor-specific antigens and used as targets for immunotherapy.

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Vorbesprechung, Rahmen- und Akteursplanungarrow. Frequently, the myeloma invades adjacent bone, destroying skeletal structures and resulting in bone pain and fractures. Occasionally, plasma cells infiltrate multiple organs and produce other symptoms. The excessive production of a monoclonal (M) protein can lead to renal failure caused by Be

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Eigene Haltung und innere Widerst?ndesorders are Waldenstrom’s macroglobulinemia, the heavy-chain diseases, primary systemic amyloidosis, and systemic light-chain deposition disease. The characteristic feature of these diseases is the involvement of cells that are either plasma cells or lymphocytes resembling plasma cells and typically

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Sprechweisen in der (Konflikt)Moderation lymphocytes all produce an identical immunoglobulin known as a monoclonal protein, the laboratory hallmark of this malignancy. Because MM is typically disseminated throughout the body at diagnosis, malignant cells must also exist, even if transiently, within the circulation as well. Although plasma