Titlebook: Biologically Based Methods for Cancer Risk Assessment; Curtis C. Travis Book 1989 Springer Science+Business Media New York 1989 assessment

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https://doi.org/10.1007/978-3-642-28515-82-Nitropropane (2-NP), methyl ethyl ketone (MEK), and n-hexane (HEX) are used in large quantities for industrial processes. They are components of solvent mixtures and are present as thinners in commercial products like glues, paints, and laquers. Because of their high volatility persons are mainly exposed via inhalation of the vapors.

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Macronutrients

Multistage Models for Cancer Risk Assessmentuch a model should have clear interpretation in biological terms and, if their dependence on dose of environmental agent can be measured or inferred, then the model can be used for low-dose and inter-species extrapolation of cancer risk.

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,The acute abdomen—case histories A to Z,en the total volume of enzyme-altered tissue in liver and the subsequent development of liver tumors have been established (Emmelot and Scherer, 1980; Kunz et al., 1983, 1985). Enzyme-altered foci are monoclonal in origin (Rabes et al., 1982; Williams et al., 1983) and show a growth advantage over t

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The Hardest Step: Succession PlanningIARC, 1986). The diagnosis of foci implies that the altered cell populations are perfectly integrated into the normal architecture of the respective tissue and do not show any expansive growth. At the histological level, preneoplasia may be defined as a phenotypically altered cell population which h