Titlebook: Biological Response Modifiers in Human Oncology and Immunology; Thomas Klein,Steven Specter,Andor Szentivanyi Book 1983 The Editor(s) (if

Calculus

Muramyl Dipeptides: Prospect for Cancer Treatments and Immunostimulationmodulating host defense mechanisms in various ways. Table 1 summarizes the activities detected by in vivo assays. The in vivo activities include the modulation (mainly potentiation) of antibody- and cell-mediated immune responses and the stimulation of reticuloendothelial system. These activities po

牽索

Clinical Phase I Investigation of Intravenous Oil Attached Mycobacterial Components as Immunotherapeignancy. Crude viable and/or killed mycobacterial agents are heterogenous preparations (2, 3), which have a significant incidence of morbidity. From an immunotherapeutic viewpoint, BCG has been shown (4, 5), in high doses, to cause splenic suppressor cells in mice, and has been implicated in causing

PAC

Immunomodulating Effects of a Short-Term Oral Treatment with C 1821 in Untreated Cancer Patients: A tration chromatography and ultracentrifugation of C 1821 yield a single peak. Its molecular weight is about 350,000. Chemical analysis has been performed by J. Montreuil and B. Fournet (Laboratory of Biological Chemistry, University of Lille I, France) and the compound is now chemically fairly well

錯(cuò)事

AORTA

Preclinical Evaluation of Lentinan in Animal Modelsal properties are strictly characterized (1-3). This polysaccharide has prominent antitumor activity in syngeneic and even autologous hosts, and its immunopharmacological characteristics are well defined as T-cell oriented immunopotentiators different from the well-known immunostimulants such as BCG

Obliterate

Immunomodulation by Small Molecular Weight Bacterial Productser (1, 2). There are many bacterial products which have been investigated in detail concerning their effects on host immunity. In this regard endotoxins derived from gram negative bacteria have been studied in much detail. There are a vast number of biological properties attributed to endotoxin, but

協(xié)奏曲

Human Macrophages May Normally be “Primed” for a Strong Oxygen Radical Response peritoneal macrophages could be enhanced at least ten-fold if the macrophages were previously “activated”. (Throughout this paper we use the term “activated” to mean “primed to release optimal amounts of O. when stimulated”). Macrophages were activated either by infecting the animals with ., strain

allergy

Sodium Diethyldithiocarbamate (Imuthiol) and Cancer of agents active on the immune system in ways that restore or regulate host defenses, has become a major objective. An overall appreciation of the published data led us to conceptualize the following requirements for suitable immunopharmacologic agents. Absence of carcinogenicity, of tumor promotin

exclamation

Michael K?lch,Paul L. Plener,J?rg M. Fegertthese have appeared and, in sum, these show that more trials are warranted (Reviewed in Ref. 1). Rather than reiterate these spotty pilot studies, I should like to consider the few key questions which should focus on the status of IFN trials.

synchronous

Michael K?lch,Paul L. Plener,J?rg M. Fegertn free from other species and other proteins simultaneously induced in human cell cultures. Comparison of the properties of different molecular species of interferon and molecular hybrids between the various species has indicated the extent to which the various biological properties of interferons m