Titlebook: Bioinorganic Chemistry; An Inorganic Perspec Dimitris P. Kessissoglou Book 1995 Springer Science+Business Media Dordrecht 1995 Base.DNA.Ino

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Methane Monooxygenasealcohol, water, and the resting diiron(III) form of the enzyme. The rate of the reaction, regioselectivity of hydroxylation, and ability to detect the intermediates spectroscopically depends upon the presence of the coupling protein. Freeze-quench M?ssbauer and low temperature stopped-flow optical s

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Copper-Zinc Superoxide Dismutase: Mechanistic and Biological Studiesby CuZnSOD .. There is a growing body of evidence indicating that oxidative damage in mammalian cells is associated with aging, carcinogenesis, and induction of other serious disease states and that toxic metabolites derived from the metabolism of O. may be responsible for such damage. Superoxide di

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Platinum Anticancer Drugsodified DNA revealed the existence of proteins that bind specifically to the major DNA adducts of the drug. These proteins, designated structure-specific recognition proteins, or SSRPs, have in common a 75 amino acid sequence known as the HMG domain which is the source of specificity for platinated

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DNA Cleavage by Cationic Metalloporphyrins to the loss of one base information and/or a break on a DNA strand which might correspond to a lethal lesion, especially when an oxidation process produces a doublestrand break (DSB), via a true DSB or via two near single-strand breaks (SSBs) on opposite strands.

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The Role of Metal Ions in Biological Systems and Medicined other metal ions by the blood plasma is achieved through the formation of protein complexes. Copper is recognized as an essential metalloelement and is primarily associated with copper-dependent cellular enzymes. Metals are also used as inorganic drugs for many diseases..The cisplatin (.-Pt(NH.).C

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1389-2185 ic Perspective of Life. give anexcellent summary of the state of the art in this field, coveringareas from the NMR of paramagnetic molecules to the use of lanthanideporphyrins in artificial batteries. .978-94-010-4113-3978-94-011-0255-1Series ISSN 1389-2185

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The Coordination Chemistry of Iron in Biological Transport and Storage; Iron Removal ,atively recent protein crystal structure information. Transferrin not only acts as a transport agent but also functions as an iron buffer, maintaining free ferric ion concentrations in the body at a very low but constant value. This role of transferrin, and our understanding of the mechanisms of iro