Titlebook: Bioinformatics for Cancer Immunotherapy; Methods and Protocol Sebastian Boegel Book 2020 Springer Science+Business Media, LLC, part of Spri

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Cell-Type Enrichment Analysis of Bulk Transcriptomes Using xCell,es to enrichment scores of 64 immune and stroma cell types across samples. Here, we described the method, discuss correct usage, and demonstrate an analysis of a cohort of peripheral blood mononuclear cells (PBMC).

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Book 2020entification and immune cell analysis from high-throughput sequencing data for cancer immunotherapy. The chapters in this book cover topics that discuss the two emerging concepts in recognition of tumor cells using endogenous T cells: cancer vaccines against neo-antigens presented on HLA class I and

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CT-angiography

Kernspin-Tomographie in der Medizines from individual mutation callers using supervised machine learning. SMuRF has improved prediction accuracy for both somatic point mutations (single nucleotide variants; SNVs) and small insertions/deletions (indels) in cancer genomes and exomes. Here, we describe the method and provide a tutorial on the installation and application of SMuRF.

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,Nasopharynx und Gesichtssch?del,es to enrichment scores of 64 immune and stroma cell types across samples. Here, we described the method, discuss correct usage, and demonstrate an analysis of a cohort of peripheral blood mononuclear cells (PBMC).

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An Individualized Approach for Somatic Variant Discovery, and inferring likelihoods from statistical models. False positives, however, are common among various tools as mismatches with the universal reference can also occur due to germline variants. Previous applications of personalized reference construction are not amenable with cancer genome analysis.

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Ensemble-Based Somatic Mutation Calling in Cancer Genomes,ogeneity in the tumors. Indeed, recent independent benchmark studies have revealed low concordance between different somatic mutation callers. Here, we describe .omatic .tation calling method using a .andom .orest (SMuRF), a portable ensemble method that combines the predictions and auxiliary featur