Titlebook: Biochemistry of Chemical Carcinogenesis; R. Colin Garner,Jan Hradec Book 1989 Plenum Press, New York 1989 Colon.DNA.Glutamat.Glutamin.bioc

capsule

,Conversion Induced by Transforming Growth Factors α and β: The Role of “Wound Hormones” in Multistaol ester treatment. Conversion can also be affected by mechanical skin wounding. It is shown that a combined injection of two putative “wound hormones”, i.e. TGFα and TGFβ, converts initiated mouse skin to a promotable state. These results indicate a close relationship between the wound response and skin tumor development.

香料

Chemical Carcinogenesis and the Primary Prevention of Human Cancer,lculating the differences between the highest and the lowest observed rates for a given site in populations which are not too dissimilar genetically. One can assume that, at least in theory, the lowest rates observed in populations where a reliable cancer registry exists, would be suitable target le

和平主義

Metabolism of Chemical Carcinogens,ble for the generation and disposition of reactive metabolites constitutes one important early contribution to the control of chemical carcinogenesis. Especially well studied is the group of enzymes responsible for the control of reactive epoxides. Many natural as well as manmade foreign compounds,

CANDY

Modify

oxidize

BALK

Arachidonic Acid Metabolites as Endogeneous Mediators of Chromosomal Alterations and Tumor Developmh the convertogenic tumor promoter TPA and promotion elicited by repetitive treatments with the irritant hyperplasiogenic phorbol ester RPA. The induction by RPA or TPA of a stationary hyperplasia seems to be a sufficient condition of promotion, cytogenic effects induced by TPA but not by RPA may be

南極

膽小鬼

啟發(fā)

Biochemsistry of DNA Repair Patch Synthesis in UV-Irradiated Permeable Diploid Human Fibroblasts,zyme responsible for repair patch synthesis in UV-irradiated human fibroblasts. UV-induced repair synthesis appears to be mediated by polymerase delta regardless of (i) the dose of UV administered, (ii) whether the damaged cells are growing or growth-arrested, or (iii) whether repair synthesis is st