Titlebook: Biochemistry and Cell Biology of Ageing: Part III Biomedical Science; J. Robin Harris,Viktor I. Korolchuk Book 2023 The Editor(s) (if appl

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Reflections on the Black Power Statement,mood, food intake, sleep, temperature and pain perception. More recent work on the CNS of invertebrate model systems has shown that 5-HT can directly regulate lifespan..This chapter will focus on detailing how CNS 5-HT signalling is altered with increasing age and the potential consequences this has on its ability to regulate lifespan.

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Conclusion: From Periphery to Foreground, histone modifications, 3D genome dynamics, and changes in the nuclear lamina. Within the chapter we discuss the implications that genome structure has on the mechanisms that drive development and ageing, and the physiological consequences when these mechanisms fail.

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Justice and the Claims of Future Generationsplay between ageing and associated diseases. In the present chapter, we have attempted to explore the information available on the role of miRNAs in ageing of various tissues/organs and diseases and understand the molecular mechanism of ageing.

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