Titlebook: Biochemistry and Cell Biology of Ageing: Part II Clinical Science; J. Robin Harris,Viktor I. Korolchuk Book 2019 Springer Nature Singapore

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Visual Defects and Ageing,on pathogenic events including oxidative damage, Mitochondrial dysfunction, endothelial alterations and changes in the visual field. These are well known in the case of glaucoma, less in the case of neurodegeneration of the brain. Many other molecular aspects are common, such as the role of endoplas

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Hutchinson-Gilford Progeria Syndrome: Challenges at Bench and Bedside,tant to maintain genome stability. Mutations in the . gene -encoding for A-type lamins- are associated with over a dozen of degenerative disorders termed laminopathies, which include muscular dystrophies, lipodystrophies, neuropathies, and premature ageing diseases such as Hutchinson Gilford Progeri

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Neurovascular Ageing and Age-Related Diseases, stiffness, autonomic dysregulation, neurovascular uncoupling and blood-brain barrier (BBB) damage will define the dynamics of brain blood flow and local perfusion. The nature and extent of ageing-related cerebrovascular changes, the degree of involvement of the heart and extracranial vessels and th

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