Titlebook: Biochemical Pharmacology as an Approach to Gastrointestinal Disorders; Basic Science to Cli Timothy S. Gaginella,Gyula Mózsik,K. D. Rainsfo

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Biochemical Pharmacology as an Approach to Gastrointestinal DisordersBasic Science to Cli

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https://doi.org/10.1057/9780230615717esicles (70 nm), and vacuoles (more than 500 nm). The granules were unaffected by α-FMH and by acute gastrin stimulation. The secretory vesicles were reduced in number by α-FMH as well as by hypergastrinaemia. The microvesicles were increased in number in response to gastrin. Vacuoles were observed

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https://doi.org/10.1057/9780230615717min) and cholera toxin (0.5 μg ml., 4 h) were administered intraluminally. Net fluid transport was determined gravimetrically..The inhibitor of NO synthetase, . -NAME, dose-dependently (0.25–50 mg kg ., iv = 5.55 μg kg.-1.11 mgkg . min .) reversed net fluid absorption to net fluid secretion. . -NAME

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https://doi.org/10.1057/9780230615717 these antagonists are not suitable for evaluation of the physiological role of galanin in this organ. In conclusion, regulation of exocrine pancreatic function is complex, involving several bioactive peptides, and this control is not completely understood, as yet. Selective receptor antagonists and

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