Titlebook: Bile Acids in Health and Disease; Update on Cholestero Tim Northfield,Riadh Jazrawi,Patrick Zentler-Munro Book 1988 Kluwer Academic Publish

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GUMP

The Secretory Defectically be kept in solution. Saturated bile is also more common among races and populations with a high frequency of gallstones., .. The development of supersaturated bile appears to be a necessary step for the subsequent precipitation of cholesterol, and may thus be considered a major risk factor fo

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The Physico-chemical Defecty were applied to cholesterol solubilisation and transport. The major (experimental) outcome was the reasonably accurate clinical definition of cholesterol saturation and supersaturation. ., the indispensable prerequisite to cholesterol crystallisation and precipitation, was the first key discovery

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Clues from Epidemiologylstones are preventable. I then look at the scope for prevention in terms of modifiable risk factors, and in terms of those eating and drinking habits which have been linked with gallstones themselves or with lithogenic bile.

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Compatriot

BUDGE

Lithotripsyiting the success of these methods has been stone size. The animal experiments of Brendel and Enders. have shown that gallstones can be fragmented . by shock-waves generated outside the body. We treated the first patients with gallbladder and bile duct stones by extracorporeally generated shock-wave

CHOP

,Isostasie und Gro?formen der Erde,different organs, the end results of which are co-ordinated physiological processes such as digestion and absorption or glucose homoeostasis. A triumph of cell biology has been the elucidation of cellular regulatory circuits, and the limiting case is that in which cells regulate their own activities

Opponent

,Isostasie und Gro?formen der Erde,n from the intestine, they have first to be taken up by the parenchymal liver cell, then transported from the sinusoidal pole to the canalicular pole of the cell, and finally secreted into the bile canalicular lumen. In addition, unconjugated bile acids have to be conjugated, chiefly with taurine or