Titlebook: Bile Acids and Their Receptors; Stefano Fiorucci,Eleonora Distrutti Book 2019 Springer Nature Switzerland AG 2019 Bile acids.Nuclear recep

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書目名稱Bile Acids and Their Receptors影響因子(影響力)




書目名稱Bile Acids and Their Receptors影響因子(影響力)學(xué)科排名




書目名稱Bile Acids and Their Receptors網(wǎng)絡(luò)公開度




書目名稱Bile Acids and Their Receptors網(wǎng)絡(luò)公開度學(xué)科排名




書目名稱Bile Acids and Their Receptors被引頻次




書目名稱Bile Acids and Their Receptors被引頻次學(xué)科排名




書目名稱Bile Acids and Their Receptors年度引用




書目名稱Bile Acids and Their Receptors年度引用學(xué)科排名




書目名稱Bile Acids and Their Receptors讀者反饋




書目名稱Bile Acids and Their Receptors讀者反饋學(xué)科排名

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Structural Insight into the Binding Mode of FXR and GPBAR1 Modulators,resenting promising pharmacological targets. We pay particular attention to the chemical and structural features of the ligand-receptor interaction, providing guidelines to achieve ligands endowed with selective or dual activity towards the receptor and paving the way to future drug design studies.

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,Pflege der Isolier?le im Betrieb,lectively target GPBAR1 or FXR..In this review, we summarize the most recent acquisition on natural, semisynthetic, and synthetic steroidal and nonsteroidal ligands, able to interact with FXR and GPBAR1.

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https://doi.org/10.1007/978-3-663-07267-6d their activated receptors in mediating the beneficial metabolic effects of bariatric surgery. We also discuss the potential to target bile acid-activated receptors in order to treat obesity and other metabolic diseases.

冷峻

The Enterokine Fibroblast Growth Factor 15/19 in Bile Acid Metabolism,he liver. However, native FGF19 seems to retain peculiar hepatic pro-tumorigenic actions. Recently engineered FGF19 analogues have been recently synthetized, with fully retained BA regulatory activity but without intrinsic pro-tumoral action, thus opening bona fide novel pharmacological strategy for the treatment of gut-liver axis diseases.

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Chemistry and Pharmacology of GPBAR1 and FXR Selective Agonists, Dual Agonists, and Antagonists,lectively target GPBAR1 or FXR..In this review, we summarize the most recent acquisition on natural, semisynthetic, and synthetic steroidal and nonsteroidal ligands, able to interact with FXR and GPBAR1.

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