Titlebook: Beta-Lactams; Novel Synthetic Path Bimal K. Banik Book 2017 Springer International Publishing AG 2017 Beta Lactams research.Synthesis antib

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,β-Lactams Through Single Bond Ring Closing: Methods, Transformations and Bioactivity,mides, the oxidative bond formation and different radical cyclizations, leading to original 2-azetidinones, including some spiro derivatives. Classical methodologies, like the use of Grignard reagents, the base-induced cyclization of β–aminoesters and the application of coupling methods to β–amino a

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Institutionalisierung politischen Handelns deal with the importance and recently developed methodologies for the synthesis of variety of heterocyclic β-lactams. Further, the biological potentials of novel heterocyclic β-lactams have also been described.

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https://doi.org/10.1007/978-3-658-01326-4o other known methods based on the condensation of 4-acetoxyazetidin-2-one with alcohols or [2?+?2] cycloaddition with chiral vinyl ethers. Particularly attractive are highly stereoselective approaches to 5-oxacephams and carbacephams which can be easily applied to solid-phase conditions.

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https://doi.org/10.1007/978-3-322-83601-4non-β-lactamic) scaffolds, as well as new heterocyclic derivatives of pyrroles, γ-lactones, γ-lactams, oxazinones, imidazolidines, piperazines, piperidines, among others. Finally, the importance of β-lactam-based hybrids as a new source of potential biologically active compounds, have been also highlighted.

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https://doi.org/10.1007/978-3-8350-5509-4 automation, among others. In this paper, recent advances of solid phase synthesis along with the stereochemistry of β-lactams (2-azetidinone) involving different resins have been discussed covering the literature up to 2015.