| 期刊全稱 | Beta-Arrestins | | 期刊簡稱 | Methods and Protocol | | 影響因子2023 | Mark G. H. Scott,Stéphane A. Laporte | | 視頻video | http://file.papertrans.cn/185/184350/184350.mp4 | | 發(fā)行地址 | Includes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts | | 學(xué)科分類 | Methods in Molecular Biology | | 圖書封面 |  | | 影響因子 | .This volume looks at various approaches to study the pleiotropic roles of b-arrestins (b-arrs) in the control of signal transduction, and the resulting cellular and in vivo consequences that arise. The chapters in this book cover diverse topics around b-arrs such as their established roles in GPCR regulation and trafficking; regulatory scaffolding functions of b-arrs in ?MAPK signaling, cAMP hydrolysis and cytoskeletal dynamics; proteomic analysis of the b-arr interactome; mathematical modelling of b-arr signaling networks; functional selectivity involving biased ligands; nucleocytoplasmic trafficking and primary cilia-associated functions of b-arrs; conformational plasticity of b-arrs; and the roles of b-arrs in allergic inflammation, Type 2 Diabetes, Parkinson’s disease, and cancer. Written in the highly successful .Methods in Molecular Biology .series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents,step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls..Cutting-edge and authoritative, .Beta-Arrestins: Methods and Protocols .is a valuable resource for resear | | Pindex | Book 2019 |
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