Titlebook: Behavioral Neurobiology of Psychedelic Drugs; Adam L. Halberstadt,Franz X. Vollenweider,David E. Book 2018 Springer-Verlag GmbH Germany, p

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Cooperative Learning in CHC Countries,l receptor mechanisms responsible for their interoceptive stimulus effects. This chapter summarizes the strengths and limitations of drug discrimination as an in vivo drug detection method and offers a brief review of historical and contemporary drug discrimination research with classical hallucinogens.

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DirectAccess and Force Tunneling,lizing a model psychosis paradigm are a step toward symptom-oriented research. Combining psychological and neurobiological techniques, the experimental psychopathological approach can provide us with a valuable tool for psychiatric research.

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ACE-inhibitor

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Hallucinogens and Serotonin 5-HT2A Receptor-Mediated Signaling Pathways,y occurring chemicals such as mescaline and psilocybin, as well as synthetic compounds, such as lysergic acid diethylamide (LSD), induce profound alterations of human consciousness, emotion, and cognition. The discovery of the hallucinogenic effects of LSD and the observations that LSD and the endog

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Interactions of Hallucinogens with the Glutamatergic System: Permissive Network Effects Mediated Th(5-hydroxytryptamine, 5-HT) and serotonergic hallucinogens induce an increase in the frequency of spontaneous excitatory postsynaptic currents (EPSCs) in the apical dendritic field by activating 5-HT. receptors. Serotonergic hallucinogens induce late EPSCs and increase recurrent network activity whe

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The Effects of Hallucinogens on Gene Expression,tions, hallucinations, detachment from reality, and mystical experiences. Some psychedelics, like LSD, are able to produce these effects with remarkably low doses of drug. Others, like psilocybin, have recently been demonstrated to have significant clinical efficacy in the treatment of depression, a

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Effect of Hallucinogens on Unconditioned Behavior,een derived from animal models. However, developing reliable animal models has proven to be a challenging task due to the complexity and variability of hallucinogen effects in humans. This chapter focuses on three animal models that are frequently used to test the effects of hallucinogens on uncondi

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Hallucinogens in Drug Discrimination,methods have proven invaluable in the evaluation and characterization of hallucinogen psychopharmacology. Used in concert with structural chemistry and receptor pharmacology methods, preclinical drug discrimination research has informed our current understanding of hallucinogens and the neurochemica