Titlebook: Behavioral Neurobiology of Huntington‘s Disease and Parkinson‘s Disease; Hoa Huu Phuc Nguyen,M. Angela Cenci Book 2015 The Editor(s) (if a

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,Modeling LRRK2 Pathobiology in Parkinson’s Disease: From Yeast to Rodents,rived induced pluripotent stem cells. We discuss how these models have contributed to understanding LRRK2 pathobiology and the advantages and limitations of each model for exploring aspects of .-associated PD.

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Book 2015ing used to study e.g. mitochondrial dysfunction in PD. This book focuses on animal models of both diseases and how they have helped and will continue to help understand the behavioral neurobiology in these disorders.

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Setting Up Research: Complications or if some inflammatory features provide protective stress responses. Here, we compare and summarize findings on neuroinflammatory responses and effects on behavior in a wide range of toxin-based, inflammatory and genetic Parkinson’s disease animal models.

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,Mouse Models of Huntington’s Disease,abnormalities in these systems impact on the behavioural readouts across the mouse lines and how these may correspond to the deficits observed in people. In addition, interpretational issues associated with the data from animal studies are discussed.

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