Titlebook: Behavioral Neurobiology of Chronic Pain; Bradley K. Taylor,David P. Finn Book 2014 The Editor(s) (if applicable) and The Author(s), under

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Neudeutung des strategischen Prozessesresulting in a significant reduction in quality of life. Pain and cognitive changes have been studied across various animal models of MS. In these models the onset of pain and cognitive dysfunction occur early, and do not coincide with the pattern of motor deficits. This is likely underpinned by a n

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https://doi.org/10.1007/978-3-663-10331-8latent pain sensitization (LS) that is masked by spinal MOR signaling for months, even after complete recovery from injury and re-establishment of normal pain thresholds. Disruption with MOR inverse agonists reinstates pain and precipitates cellular, somatic, and aversive signs of physical withdrawa

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