Titlebook: Basic Epithelial Ion Transport Principles and Function; Ion Channels and Tra Kirk L. Hamilton,Daniel C. Devor Book 2020Latest edition The A

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Principles of Epithelial Transport,ield or an outline of what to teach to beginning students. Most of the general principles introduced here are described in detail in later chapters of this book. Epithelial transport is an ideal subject for teaching basic biological concepts (for example, electrical and chemical gradients) and for c

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Molecular Mechanisms of Apical and Basolateral Sorting in Polarized Epithelial Cells,epithelia. Polarized sorting is achieved through elaborate intracellular sorting pathways encompassing the .-Golgi network, early endosomes, and recycling endosomes that are fine-tuned for epithelial function and thus different from the secretory and endocytic systems in non-polarized cells. Polariz

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Membrane Protein Structure and Folding, to form these ordered structures is encoded in the polypeptide chain. Questions related to the mechanisms of protein folding for both soluble and transmembrane proteins remain a large field of research utilizing a combination of biochemical, biophysical, genetic, and large-scale computational appro

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Epithelial Ion Channel Folding and ER-Associated Degradation (ERAD),s are tightly regulated at both the transcriptional and posttranscriptional levels. For example, ion channel residence at the plasma membrane is regulated in response to intra- and extracellular signals that can alter anterograde trafficking, endocytosis, and/or degradation. While regulation at the

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Volume Regulation in Epithelia,volume and osmolyte concentrations that would be critical to normal function if not regulated. The studies have been challenged by the fact that epithelia may contain more than one cell type, and by the large osmotic permeability of some epithelial membranes that presupposes successful elimination o