Titlebook: Application of Nanocarriers in Brain Delivery of Therapeutics; Amit Alexander Book 2024 The Editor(s) (if applicable) and The Author(s), u

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In Vitro Cell Line Culture for Brain Research and Its Limitations,cell line models for brain research. These models encompass a wide array of neuronal and glial cell lines, primary cultures, and sophisticated systems that closely mimic the brain’s intricate microenvironments. They have become invaluable tools for investigating various facets of brain biology and p

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Safety, Stability Concerns, and Regulatory Aspects of Nanocarriers for Brain Delivery,he nanocarriers derived from metals, polymers, and other materials have shown their therapeutic efficacy against several neurological disorders during in vitro and preclinical studies. However, these nanocarriers, especially metal and silica NPs, have shown their toxicity against neuronal cell lines

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Current Clinical Advancements of Nanocarriers for Brain Targeting and Limitations in Clinical Trans drug targeting, minimized side effects, improved drug efficiency, and patient compliance, nanocarriers take upper hand. Successful translation of research hypothesis led to clinical availability of a good number of nanomedicines intended for a range of physiological conditions like kidney dysfuncti

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Application of Nanocarriers in Brain Delivery of Therapeutics

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Application of Nanocarriers in Brain Delivery of Therapeutics978-981-97-2859-6

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https://doi.org/10.1007/978-94-015-8175-2n disorders. However, bioactives have low bioavailability, poor solubility, and inefficient delivery because of blood-central nervous system barriers. To overcome these issues, a lipid nanocarrier system was found to be a suitable strategy for delivering these bioactives. This chapter discusses lipo