Titlebook: Autophagy; Methods and Protocol Nicholas Ktistakis,Oliver Florey Book 2019 Springer Science+Business Media, LLC, part of Springer Nature 20

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,Einstein’s Law of Gravitation, in neurons are only beginning to be understood. To address this fundamental gap in knowledge, we have established several key methodologies for live-cell imaging and quantitative analysis of autophagy in primary hippocampal neurons. Using these methods, we have defined compartment-specific dynamics

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Formation of Autophagosomes Coincides with Relaxation of Membrane Curvaturerecursors and report that the formation of autophagosomes is associated with a strong relaxation of membrane curvature energy. This effect we find for a wide range of membrane asymmetries. It is especially strong for small distances between both autophagosomal membranes, as observed in vivo. We quan

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