Titlebook: Autonomic Innervation of the Heart; Role of Molecular Im Riemer H.J.A. Slart,René A. Tio,Markus Schwaiger Book 2015 Springer-Verlag Berlin

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The Autonomic Nervous System of the Heart,yocardial cells, as well as of coronary vascular tone and myocardial blood flow. The sympathetic system promotes an increase in heart rate and a positive inotropic response in order to increase cardiac output. On the contrary, the parasympathetic (vagal) system induces bradycardia and reduces myocar

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Development of Heart Failure and the Role of the Autonomic Nervous System of the Heart,gue and dyspnea being major barriers for exercise tolerance. Medication, in particular beta-blocker and ACE-inhibitor therapy, influences both the sympathetic and parasympathetic tone. The sympathetic tone may also be modulated by cardiac resynchronization therapy whereas vagus nerve stimulation may

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Tracers for Sympathetic Cardiac Neurotransmission Imaging, pathway), postsynaptic α- and β-adrenoceptor density, and second messenger systems (adenylate cyclase/cyclic adenosine monophosphate (cAMP) and phospholipase C/inositol trisphosphate cascades). While the majority of clinical applications to date have utilized analogues of norepinephrine including .

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,PET Imaging of Myocardial β-Adrenoceptors, main limitation of [.C]-CGP-12177 and [.C]-CGP-12388, besides the troublesome production of the former, is the lack of subtype selectivity. Future perspectives may include the development of subtype-selective β-adrenergic receptor ligands to obtain more information about the pathophysiological role

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Autonomic Imaging in Myocardial Ischemia,edrine (mHED) is particularly useful when regional assessment of sympathetic nerve function is of concern such as those encountered in CHD. However, inconsistent autonomic imaging results have been published in vasospastic angina, silent myocardial ischemia, and reinnervation after myocardial infarc