Titlebook: Atypical Antipsychotics; Bart A. Ellenbroek,Alexander R. Cools Book 2000 Springer Basel AG 2000 dopamine.research.schizophrenia.serotonin.

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Jochen Ludewig,Martin Glinz,Hans Matheise stimulation of dopamine D2—type receptors plays a role in the positive symptoms of schizophrenia whereas imbalance in the stimulation of excitatory 5-HT.receptors may be involved in the expression of some of the negative symptoms of schizophrenia, and defective signalling of N-methyl-D-aspartate (

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https://doi.org/10.1007/978-3-642-70639-4t necessarily had to induce extrapyramidal side-effects [.-.], see also Naber et al., this volume. This drugs seems to be almost completely free of extrapyramidal side-effects, including tardive dyskinesia.

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https://doi.org/10.1007/978-3-030-59872-3 introduction in 1960 in that the neuroleptics produced catalepsy in rodents and EPS in man at clinically relevant doses and clozapine did not [.]. This term was widely used by preclinical investigators to refer to clozapine in their efforts to understand the biological basis for the difference betw

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Book 2000d anhedonia, and secondly virtually all antipsychotics produced a number of side-effects, of which the neurological (often called extra- pyramidal) side-effects were the most troublesome. Especially the tardive dyskinesia, which occurred in about 15 to 20% of the patients after pro- longed treatment