Titlebook: Attempts to Understand Metastasis Formation I; Metastasis-Related M Ursula Günthert,Walter Birchmeier Book 1996 The Editor(s) (if applicabl

majestic

Arnd Hartmanns,Bram Kohlen,Peter Lammichand assemble the components of the ECM whereas the ECM stabilizes the physical structure of tissues and also regulates the behavior of cells (. 1988, . and . 1993). Transformed cells can alter the composition and structural integrity of adjacent matrix promoting tumor progression. Enzymes produced b

semiskilled

A Local Search Algorithm for?MaxSMT(LIA)cell-cell and cell-matrix contacts are likely to influence both normal responses (e.g. wound healing) and abnormal processes (e.g. malignant transformation). The glycoprotein SPARC (secreted protein, acidic and rich in cysteine), also termed osteonectin, BM-40, and 43 K protein, has been classified,

V切開

Loes Kruger,Sebastian Junges,Jurriaan Rotew properties (. and . 1982; . and . 1992). The identification of molecules which are newly expressed, altered or lost during this process can lead to an understanding of the molecular basis of tumor progression and metastasis formation and can also lead to the development of diagnostic and therapeu

phytochemicals

Soaibuzzaman,Jan Oliver Ringertrly events include a loosening of cell-cycle control and disabling of checkpoints and failsafe mechanisms such as cell-cell constraints on proliferation and motility (. et al. 1992; . and . 1990). Successfully metastatic cells arising from this population display an altered repertoire of cell adhesi

GRIEF

Stefan Hallerstede,John Hatcliff,Robbyut penetrate into the surrounding normal tissues. On their way to lymph or blood vessels they create a path of destruction. This invasive behavior eventually gives access to the circulation, and opens a gate to metastatic dissemination(. et al.; . and . 1982; . et al. 1993).

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Soaibuzzaman,Jan Oliver Ringertn the mouse skin system, for example, the loss of epithelial differentiation is accompanied by the appearance of malignant properties. In this well-studied system, chemical carcinogenesis generates multiple benign tumors, a proportion of which develop to form squamous cell carcinomas and, in extreme

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Eduard Baranov,Axel Legay,Martin Viviane morphogenesis and organogenesis and are involved in the maintenance of organ structures (. 1990;. 1992a; . and . 1993; . et al. 1993). Adhesion molecules are of the utmost importance for most functional activities of the immune system (. 1990; . and . 1991; . et al. 1992; . 1992; . 1992; . et al.