Titlebook: Atlas of Liquid Biopsy; Circulating Tumor Ce Ludmilla Thomé Domingos Chinen Book 2021 Springer Nature Switzerland AG 2021 Circulating tumor

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Circulating Tumor Cells in Mesenchymal Tumors,ies involving CTCs from mesenchymal tumors and mesenchymal-epithelial transition. It may open an area for future investigations and better understanding about CTCs and epithelial mesenchymal transition.

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Circulating Tumor Microemboli: Characteristics and Clinical Relevance,g biological, functional, physical-chemical aspects of these – not so long ago unknown – group of cells, and the influence on tumor growth, failure in the systemic treatment, and consequently disease relapse or progression to metastasis. We will discuss all these topics here.

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Giant Macrophages: Characteristics and Clinical Relevance, response, and the important role TAMs play in metastasis. Macrophages as therapeutic targets will also be discussed. Finally, the concept that macrophages can physically interact with CTCs or fuse with tumor cells to create giant macrophages or cell fusions that are invisible to the immune system a

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,In Vitro and In Vivo Models of Circulating?Tumor Cells,sed for preclinical evaluation medicines, identification of biomarkers, biological studies, and personalized medicinal strategies. In this chapter, we discuss the basic knowledge of CTCs and demonstrate some of the existing CTC-derived models, including in vivo CDXs and PDXs and in vitro functional

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Book 2021nosis as a feasible tool. In this context, it is of the utmost importance to know the morphology and characteristics of CTCs to determine a correct diagnosis. Currently much of the scientific community is committed to expanding our knowledge of CTCs, and this work makes a valuable contribution, pres

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