Titlebook: Asbestos and Mesothelioma; Joseph R. Testa Book 2017 Springer International Publishing AG 2017 Asbestos.Cancer Prevention.Cell Signaling.E

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,Allgemeine Theorie der Tauschvertr?ge,e efficacy of therapies. The promise of precision medicine is to improve human health by combining biomarkers with clinical data. Therefore, the discovery of gene signatures correlated to clinical characteristics is fundamental to identify patients that can benefit from a specific treatment. Althoug

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Allgemeine Theorie der Intermediation,val. These models, both in vitro and ex vivo. may be ideally suited for studying mesothelioma. Here we discuss the reports that are currently available on this subject and highlight areas in which 3D biology may provide insights into the mechanisms of cell death and survival in mesothelioma. It has

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https://doi.org/10.1007/978-3-322-86735-3 of cases globally and the substantial geographic distribution of patients, large randomized clinical trials were difficult and lengthy to complete, and thus, interest from pharmaceutical companies was limited. Additionally, financial support from various funding agencies is limited for this orphan

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https://doi.org/10.1007/978-3-322-97681-9hanisms to promote immune tolerance and to escape host immune surveillance. These include immune checkpoints—molecules expressed on the surface of immune cells and tumor cells—that curb effector T-cell responses. The emerging category of drugs that inhibit immune checkpoints and their ligands have s

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