Titlebook: Artificial Oxygen Carrier; Its Frontline Koichi Kobayashi (Chief Professor of Surgery),Eish Conference proceedings 2005 Springer-Verlag Tok

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Isolation and Culture of Skin Fibroblastsing a hemoglobin (Hb)-based oxygen carrier. In this chapter, we have summarized the characteristics and performances of Hb-vesicles (HbV) that have been developed on the basis of molecular assembly. Collaborative in vitro and in vivo studies have revealed sufficient safety and efficacy of HbV.

ACME

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ETCH

https://doi.org/10.1007/978-3-319-98143-7ric oxide (NO) [Yonetani et al., (1998) J Biol Chem 273: 20323], have shown that the α-nitrosyl HbA is a cooperative, low-affinity oxygen carrier. We have developed a simple method to convert all the intra-human red blood cells (RBCs) to a 50% saturation of hemes with NO exclusively bound to the α-s

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Merry L. Lindsey,Lisandra E. de Castro Brás-heme, is an entirely synthetic hemoprotein that can reversibly bind and release O. under physiological conditions. We have recently found that replacing the substituent groups of FepivP with more hydrophobic 1-methylcyclohexanoylamino groups, affording FecycP, substantially stabilizes the formed O.