Titlebook: Arachidonic Acid in Cell Signaling; Daniele Piomelli Book 1996 Springer Science+Business Media Dordrecht 1996 biochemistry.cell.chemistry.

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Book 1996xygenated metabolites that may act as second messengers or as local mediators), and anandamide (an endogenous cannabinoid substance). Dysfunctions in the arachidonic acid cascade underlie a number of serious pathological conditions, making these biochemical pathways the target for drugs of clinical value.

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https://doi.org/10.1007/978-88-470-3983-4vates a specific protein kinase, protein kinase A, which phos-phorylates select intracellular proteins. Phosphorylation modifies the biological activity of these proteins and forms the basis for many physiological effects of dopamine in the central nervous system..

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https://doi.org/10.1007/978-88-470-3961-2 criteria, listed in Table 3.1, are based on the definition of a second messenger as an endogenous molecule whose role is to transduce within a target cell the actions of a hormone, a neurotransmitter or any other extracellular signaling substance (i.e., a ‘first messenger’).

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Before Metabolism: Arachidonate as an Intracellular Second Messenger, criteria, listed in Table 3.1, are based on the definition of a second messenger as an endogenous molecule whose role is to transduce within a target cell the actions of a hormone, a neurotransmitter or any other extracellular signaling substance (i.e., a ‘first messenger’).

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