Titlebook: Aptamers in Biotechnology; Katharina Urmann,Johanna-Gabriela Walter Book 2020 The Editor(s) (if applicable) and The Author(s), under exclu

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https://doi.org/10.1007/978-3-030-54061-6Chemical Antibodies; Aptamer-based Biosensors; Aptamer-based Diagnostics; Aptamer-based Affinity Chroma

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978-3-030-54063-0The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl

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Biophysical Characterization of Aptamer-Target Interactions,d specificity. They are capable of interacting with various kinds of ligands: ions, small molecules, peptides, proteins, viruses, bacteria, and even cells. Therefore, aptamers are in widespread use as sensor molecules or as targeting agents in diagnostics and pharmaceutics. As a prerequisite for the

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Impedimetric Aptamer-Based Biosensors: Principles and Techniques,th impedance spectroscopy as sensitive measurement method, we gain a class of biosensors with high potential for handheld devices and point-of-care tests. In this review, we report on recent advances in aptamer-based impedimetric biosensors. Besides giving a short summary of electrochemical measurem

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Aptamers in Diagnostic and Molecular Imaging Applications,atment, and prognosis, even following therapy. An early and correct diagnosis is necessary for an efficient treatment. Moreover, it is possible to predict if and why a therapy will be successful or fail, enabling the timely application of alternative therapeutic strategies. Available diagnostics are

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Aptamer-Modified Nanoparticles in Medical Applications,es, aptamer-modified nanoparticles can be used in various diagnostic and therapeutic applications. While the aptamer is responsible for specificity and affinity of the conjugate, the nanoparticles’ function varies from signal generation in diagnostic approaches to drug loading in drug delivery syste

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