Titlebook: Approaching Complex Diseases; Network-Based Pharma Mariano Bizzarri Book 2020 Springer Nature Switzerland AG 2020 Efficiency of multi-targe

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,Targeting the Tumor-Associated Macrophages for ‘Normalizing’ Cancer,heir functional programming. Here, we discuss modern immunotherapeutic approaches of targeting tumor-infiltrating macrophages including inhibition of the recruitment of monocytes to the tumor, activation of apoptosis in macrophages, repolarization, based on the inhibition of pro-tumor activity or st

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Tumor Reversion Induced by Embryo and Oocyte Extracts,ing a number of prominent aspects of malignancy. Theoretical models have established a useful theoretical framework able to explain insights into the complex interactions taking place between cancer cells and morphogenetic fields, nevertheless a large research effort must be carried out in order to

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Trabectedin, a Drug Acting on Both Cancer Cells and the Tumor Microenvironment, with encouraging results. Nevertheless, targeting only the tumor-promoting macrophages may not be sufficient to definitely eradicate cancer. The finding that the anti-tumor agent trabectedin has wider mechanisms of action than previously perceived, opened novel interesting viewpoints. Trabectedin p