Titlebook: Approaches in Integrative Bioinformatics; Towards the Virtual Ming Chen,Ralf Hofest?dt Book 2014 Springer-Verlag Berlin Heidelberg 2014 Bi

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Methodische und methodologische Reflexion,types of RNA involved in a given response or process. Such a range of data will be necessary to unravel the complexities of the multiple layers involved in the regulation of gene expression..In this article we discuss a broad range of studies about gene regulation. These involve studies of processes

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Erfolg als theoriegeleitete Kategorie, of databases, repositories and ontologies. These data repositories differ substantially in granularity of data, storage formats, database systems, supported data models and interfaces. In order to make full use of available data resources, the high number of heterogeneous query methods and frontend

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Das situative Forschungskonzept, of scientific publications. Gaining access to this knowledge can prove difficult as each database may provide different tools to query or show the data and may differ in their structure and user interface or uses a different interpretation of biological knowledge than others. Systems approaches to

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https://doi.org/10.1007/978-3-322-82282-6tems biology. Biological networks as representations of such processes are crucial for an extensive understanding of living beings. Due to their size and complexity, their growth and continuous change, as well as their compilation from databases on demand, researchers very often request novel networ

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Biologische Blockaden erkennen und besiegen,a is the creation of a virtual cell. Naturally, this topic is accompanied by a vast amount of problems which arise due to the fact that a large number of highly specific disciplines have to be addressed. In this publication a subproblem will be discussed, functional cell modeling. Beginning with a v

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https://doi.org/10.1007/978-3-322-82445-5A central goal of current biology is to establish complete functional links between the genome and phenome, the so-called genotype–phenotype map. Recent advances in high-throughput and high-dimensional genotyping and phenotyping technologies enable us to uncover the casual networks inside the “black