Titlebook: Applied Toxicology: Approaches Through Basic Science; Proceedings of the 1 Jürg P. Seiler,Eugenio Vilanova Conference proceedings 1997 Spri

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Deepak N. Pandya,Douglas L. Rosenel., 1991; Harris, 1993; Levine, 1995; Ko and Prives, 1996; Jacks, 1996; Arrowsmith and Morin, 1996). For epidemiologists and toxicologists, an interesting feature of p53 is that the specific mutation patterns correlate with the inducing agent, i.e. tobacco smoke will result in other types of lesions

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Douglas R. Nordli Jr.,Darryl C. De Vivoably intact, though it blebs and the phospholipids redistribute. The specific translocation of phosphatidylserine to the outer leaflet of the plasma membrane has been shown to play a very important role in the recognition of apoptotic cells by phagocytes (Martin et al., 1995). In addition, other mem

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James E. Rubenstein,Eileen P. G. Viningfor the immunotoxic outcome (altered gene expression). It has been demonstrated that the formation of DNA photoproducts by UV light is associated with the activation of many genes. Several studies indicate that UV-induced DNA damage, in the form of cyclobutyl pyrimidine dimers plays a role in UV-ind

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Comparison of Methods for Seizure Detection,ment are predicted more realistically. The GREAT-ER project (Geography-referenced Regional Exposure Assessment Tool for European Rivers) was launched to refine regional and local exposure assessments for down-the-drain chemicals by applying real, spatial-referenced datasets instead of generic or ave

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Genetic Polymorphism of Drug Metabolizing Enzymes. Implications for Toxicity of Drugs and Other Xenoenetic polymorphism of the corresponding genes, as well as to physiological-, environmental- and pathological factors. From a teleological point of view it is evident that genetically based interindividual variability is seen in the human lymphocyte antigen (HLA) system, the immune system and in the

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Toxicologists versus Toxicological Disasters: Toxic Oil Syndrome, Clinical Aspectstry. The majority of cases were diagnosed during May, June and July of that year, with only a few documented at later dates, including one as long as a year after the epidemic outbreak (Posada, 1989). Neither clinically nor pathologically had any such disease been previously recognized, nor had its

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Epidemiology of the Toxic Oil Syndromepeseed oil could be legally imported for industrial use. Denaturation of imported food oils with castor oil, methylene blue, or aniline was required by Spanish law and indicated that the oil was intended for industrial use due to undesirable properties of the denaturants.

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