Titlebook: Applied Statistics in Biomedicine and Clinical Trials Design; Selected Papers from Zhen Chen,Aiyi Liu,Yi Tsong Conference proceedings 2015

ATRIA

Kindle

無(wú)可爭(zhēng)辯

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Nonparametric Covariate Adjustment for the Youden Indexpular summary index of the ROC curve. In some diagnostic studies, it is believed that the impact of covariates might influence the accuracy of the diagnostic test. In regards to this consideration, we propose nonparametric estimates for the YI with covariate adjustment for the test results under het

Nonporous

大暴雨

ethereal

Collective Evidence in Drug Evaluationicity adjustments within one study to control the type I error rate. The use of multiplicity adjustment procedures (MAPs) sometimes leads to conclusions that may not seem logical. As drug efficacy evaluation involves aspects such as assessing efficacy, selecting optimal doses, and labeling claims, i

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爵士樂(lè)

Inferiority Index, Margin Functions, and Hybrid Designs for Noninferiority Trials with Binary Outcomiateness of a fixed margin. The two-step fixed margin approach recommended in the Food and Drug Administration (FDA) guidance to industry on NI trials (US FDA, Guidance to industry: non-inferiority clinical trials, 2010) relies on the availability of relevant historical data and expert clinical know