Titlebook: Applications of Pharmacokinetic Principles in Drug Development; Rajesh Krishna Textbook 2004 Kluwer Academic/Plenum Publishers, New York 2

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H. Schumacher,N. Diehm,J. R. Allenbergtrates a direct pharmacological interaction in which a meal component alters clinical response to oral drug administration dictating marketed product insert warnings and special prescription labeling.

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Bioanalytical Methods: Challenges and Opportunities in Drug Development, both drugs and putative metabolites in biological matrices such as blood, plasma, serum and urine. Additionally, significantly greater attention is being focused on the metabolic liabilities of these compounds at earlier stages in drug development than ever before. In a continuing effort to keep up

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