Titlebook: Antiviral Drug Discovery and Development; Xinyong Liu,Peng Zhan,Vasanthanathan Poongavanam Book 2021 The Editor(s) (if applicable) and The

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An Update on Antiretroviral Therapy, efforts during the last 40?years have led to the approval of over 30 antiretroviral drugs and the introduction of combination therapies that have turned HIV infection into a chronic but manageable disease. In this chapter, we provide an update on current available drugs and treatments, as well as f

Mercurial

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Moving Fast Toward Hepatitis B Virus Elimination,(pegylated or non-pegylated). These treatments can control viral replication and improve survival; however, they do not eliminate the virus and therefore require long-term continued therapy. In addition, there are significant concerns about virus rebound on discontinuation of therapy and the develop

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Discovery and Development of Antiviral Therapies for Chronic Hepatitis C Virus Infection,stage of HCV infection, 18–34% of individuals exhibit spontaneous clearance. However, the remaining 66–82% of infected individuals progress to chronic HCV infection and are at subsequent risk of progression to hepatic fibrosis, cirrhosis, and hepatocellular carcinoma (HCC). Chronic hepatitis C progr

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漂亮

Anti-Influenza Drug Discovery and Development: Targeting the Virus and Its Host by All Possible Mea prevention and treatment of influenza virus infection and disease. Today, the number of antiviral molecules approved for the treatment of influenza is relatively limited, and their use is threatened by the emergence of viral strains with resistance mutations. There is therefore a real need to expan

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