Titlebook: Antiviral Drug Development; A Multidisciplinary Erik Clercq,Richard T. Walker Conference proceedings 1988 Plenum Press, New York 1988 anti

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The European Public Sphere and the Internetr the prophylaxis and early treatment of influenza A virus infections, idoxuridine, trifluridine, vidarabine and acyclovir for the topical treatment of herpetic keratitis, acyclovir for the systemic (intravenous or peroral) treatment of herpes simplex virus (HSV) and varicella-zoster virus (VZV) inf

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Electronic Density Functional Theoryshortcomings of this so-called . testing are obvious: substances which lack an effect on the viral replication cycle but, e.g., enhance antibody formation, improve nonspecific resistance, strengthen the interferon systems will not be detected by this method. Likewise, although so far only rarely des

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John P. Perdew,Matthias Ernzerhofnot be understated. While tissue culture systems are of great value in determining if a new drug has activity against a particular virus, these systems should not be used as indicators or predictors of activity in humans. Only where suitable animal models are not available, should a compound be take

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Rachel Y. W. Lau,Hilary J. Kahnral, it manifests itself as tissue immunity. That means that a tissue infected with a virus is resistent to infection with other types of viruses. This phenomenon was already described in the beginning of this century, not only between antigenically related viruses such as yellow fever viruses (1) a

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Schema Evolution in the STAR Frameworkvents that are unique and to identify compounds that have the potential to interfere with these events. The available new antiviral agents have already impacted upon the treatment of several viral illnesses and more are under development. With the advent of compounds that interrupt or interfere with

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Communication in a Distributed Environmentreased knowledge on antiviral drugs, but more importantly, one of attitude. The prevailing skepticism of the past has given way to optimism and determination. This determination is partially due to recent successes in the field, but more likely results from the acquired immunodeficiency syndrome (AI