Titlebook: Antitumor Antibiotics; S. K. Carter (Director),Hamao Umezawa (Head),Yoshi Book 1978 Springer-Verlag Berlin · Heidelberg 1978 antibiotics.c

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Experimental Results with the Combination of Bleomycin Plus Mitomycin C,Bleomycin, a water-soluble basic glycopeptide antibiotic, is well known for treatment against human squamous cell carcinoma and malignant lymphoma [4, 5, 14, 17]. Recently, Miyamoto et al. reported that a sequential combination of bleomycin and mitomycin C induced a drastic remission effect on advanced cervical cancer [7].

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Role of Antitumor Antibiotics in Current Oncologic Practice,course of this discussion, we will present specific points to aid the future development in this important area. Table 1 lists the agents to be described and the areas in which they have exhibited a major impact in clinical practice.

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In Vivo Antitumor Evaluation of Antibiotics. Selected Results from the Drug Evaluation Program of t(DCT), National Cancer Institute (NCI) examined over 1000 fermentation broths for activity against one or more animal tumors. The yield of “active” materials from this in vivo screening program are presented elsewhere in this volume [2].

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Rechtliche Aspekte des Electronic Commerceof this screening technique to eliminate knowns as quickly as possible in the early stages of the program has been very successful; it has increased the efficiency of our overall program. The purpose of this paper is to present some of the details of our “fingerprint” techniques.

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Torsten Tomczak,Marcus Sch?gel,Ben Birkhoferologic toxicity. It was concluded that mitomycin C had an extremely narrow therapeutic index, while demonstrating only limited efficacy. The result was a sharply reduced interest for mitomycin C as an anticancer agent in the United States.

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Fingerprint Methods used to Identify known Antineoplastic Agents in Culture Filtrates,of this screening technique to eliminate knowns as quickly as possible in the early stages of the program has been very successful; it has increased the efficiency of our overall program. The purpose of this paper is to present some of the details of our “fingerprint” techniques.

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