Titlebook: Antineoplastic and Immunosuppressive Agents; Part I Alan C. Sartorelli (Professor),David G. Johns Book 1974 Springer-Verlag Berlin · Heidel

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https://doi.org/10.1007/b113784tially sensitive to chemotherapy, either in the sense that a sizeable number of patients show some degree of regression of disease, or that a few patients will show a substantial degree of regression. There are now over 30 drugs that are available for the chemotherapy of cancer. Even though some of

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Stochastic Approach to Nucleation,ainst clinical neoplasia, (b) the detailed investigation of the action of drugs on host-tumor parameters and of factors which may influence chemotherapeutic effectiveness, and (c) detailed pharmacologic, toxicologic, biochemical, virologic, immunologic, and other investigations of the basic mechanis

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Kinetics of Electrochemical Nucleation,98), and the application of this class of compounds to the treatment of human cancers was introduced by . and . (1946). This followed the observation that derivatives of mustard gas such as HN2 (nitrogen mustard, I) were particularly toxic towards lymphoid tissue . and led to the use of such agents

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Electrochemical Crystal Growth,the invading cancer cells. Although much is known about the biologic activity of certain agents, such as 6-mercaptopurine and 6-thioguanine, the basis of their selective action on cancer cells is still not fully understood. This selectivity could result from greater catabolism of the drug by normal

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