Titlebook: Antimutagenesis and Anticarcinogenesis Mechanisms; Delbert M. Shankel,Philip E. Hartman,Gregory Kuny Book 1986 Springer Science+Business M

令人心醉

木質(zhì)

Antimutagens and their Modes of Actioncellular mutagenesis (19, 22). The word antimutagen has an old origin and has been adopted for factors that reduce the rates of spontaneous and induced mutagenesis by different modes of action. We recently pro-posed a distinction among categories of antimutagens (20, 22) (Fig. 1) as follows:

incite

https://doi.org/10.1007/978-1-4684-2058-6n enter the target cell. Antimutagenesis then becomes either the enhancement of the nonmutagenic repair of DNA, the inactivation of mutagenic repair, the inactivation of the SOS repair processes, or some interference with the expression of mutations.

Mortal

Theme and Objectives of the Conferencein the liver (5). For this reason, many pioneering studies on the activation or inactivation of carcinogens, mutagens, and other drugs have been carried out using hepatic microsomes from various animal models. In turn, mammalian liver also was used in attempts to isolate, purify, and characterize components of the mixed-function oxidase system.