Titlebook: Antimicrobial Compounds; Current Strategies a Tomás G. Villa,Patricia Veiga-Crespo Book 2014 Springer-Verlag Berlin Heidelberg 2014 Anti-fu

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The Cornerstone of Nucleic Acid-Affecting Antibiotics in Bacteria,al compounds block RNA synthesis by specific inhibition of bacterial RNA polymerase without interacting with mammalian analog enzymes. Others, such as actinomycins or doxorubicin, interfere with transcription in both bacterial and mammalian systems and may be used as antitumor drugs because the fast

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Genetic Analysis and Manipulation of Polyene Antibiotic Gene Clusters as a Way to Produce More Effesis, immunosuppressive therapy, cancer chemotherapy, or the use of broad-spectrum antibiotics contribute to the boost of such patient category. However, progress in the treatment of fungal infections has been slow. Different polyenes and/or azoles are available for the treatment of systemic fungal i

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Perspectives in the Research on Antimicrobial Peptides,les can be synthesized in chemical laboratories covering in principle an unlimited extension of chemical structures, sequences, and spectra of action. The use of peptides as antimicrobials has been relatively extended in industrial microbiology. Lantibiotics and bacteriocins from lactic bacteria hav

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