Titlebook: Antimalarial Drug II; Current Antimalarial Wallace Peters (Professor of Medical Protozoology) Book 1984 Springer-Verlag Berlin Heidelberg 1

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Electric and Plug-In Hybrid Vehiclesfor clinical use. The possible value of drug combinations in the prevention of drug resistance will be covered in Chap. 16. Combinations of drugs may be considered under several headings, namely those that are complementary (e.g. against different stages of a parasite), combinations that are additiv

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Vehicle Dynamics and Performance,ease have been addressed in various sections of this volume. We propose to discuss here a specific need which exists in malaria chemotherapy, that is for agents with prolonged activity — the so-called repository drugs. This therapeutic requirement has only in recent years received attention, and it

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Vehicle Dynamics and Performance, liver forms of . and . (. 1980). The clinical use of PQ as a causal prophylactic and therapeutic agent is, however, curtailed by its toxic side effects, especially for those patients having glucose-6-phosphate dehydrogenase-deficient erythrocytes (. et al. 1962). Much research has, therefore, been

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Electric, Hybrid, and Fuel Cell Vehiclesustomary to refer to them as derivatives of methanol and they are further classified according to their particular aromatic ring system, e.g. quinolinemethanols, phenanthrenemethanols, pyridinemethanols, etc. Since all of the arylaminoalcohols discussed in this chapter were developed in the US Army

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https://doi.org/10.1007/978-3-642-54839-0 the most part, considered only those drugs or compounds that have shown an activity sufficient to focus broad attention upon them. Because established drugs are discussed elsewhere in this volume (see Chap. 1), much of the discussion in this chapter will centre on research and development efforts t

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https://doi.org/10.1007/978-3-642-54839-0he classic drugs remains unclear. However, substantial knowledge has been collected on the parasite folic acid cycle (see Part I, Chap. 2) and on those structures which exert their antimalarial effects via its inhibition. Thus the sulphonamides and the so-called antifolates act on the synthesis of f