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Titlebook: Antiepileptic Drugs; Pharmacology and The Mervyn J. Eadie,Frank J. E. Vajda Book 1999 Springer-Verlag Berlin Heidelberg 1999 catecholamines

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樓主: Abridge
21#
發(fā)表于 2025-3-25 04:14:43 | 只看該作者
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發(fā)表于 2025-3-25 08:17:30 | 只看該作者
23#
發(fā)表于 2025-3-25 13:32:51 | 只看該作者
Werkzeuge für die Werkstoffverarbeitungers. Since then phenytoin has been one of the mainstays of seizure therapy. In 1968 . et al. reported success in the treatment of status epilepticus with high doses of phenytoin given intravenously. A water-soluble prodrug was developed in the 1980s to simplify the parenteral administration of phenytoin (see Sect. B on fosphenytoin, below).
24#
發(fā)表于 2025-3-25 19:02:43 | 只看該作者
25#
發(fā)表于 2025-3-25 20:29:06 | 只看該作者
26#
發(fā)表于 2025-3-26 02:23:38 | 只看該作者
Phenytoin and Congeners,ers. Since then phenytoin has been one of the mainstays of seizure therapy. In 1968 . et al. reported success in the treatment of status epilepticus with high doses of phenytoin given intravenously. A water-soluble prodrug was developed in the 1980s to simplify the parenteral administration of phenytoin (see Sect. B on fosphenytoin, below).
27#
發(fā)表于 2025-3-26 06:52:05 | 只看該作者
Vigabatrin,e in water but only slightly soluble in ethanol and methanol and is insoluble in hexane and toluene. It is a white to off-white crystalline solid with a melting point of 171°–177°C. Its molecular weight is 129.16 and the conversion factor (CF) is 7.75 (mg/l × CF = μmol/l).
28#
發(fā)表于 2025-3-26 09:12:22 | 只看該作者
Tiagabine,Abbott Laboratories filed a new drug application for tiagabine with the Food and Drug Administration in the United States for its use as add-on therapy for partial seizures and the drug was approved September, 1997.
29#
發(fā)表于 2025-3-26 15:59:07 | 只看該作者
Book 1999 were previously. As well, more information is available concerning the natural history of human epilepsy, and this knowledge is important in making optimal use of the various agents that are now available. Therefore, it has seemed appropriate at this stage in the evolution of knowledge to produce a
30#
發(fā)表于 2025-3-26 19:17:47 | 只看該作者
Manfred Wick,Wulf Pinggera,Paul Lehmannth, certain models can be used to study mechanisms of drug resistance in epilepsy. Sixth, in view of the possibility that chronic brain dysfunction, such as epilepsy, might lead to altered sensitivity to drug adverse effects, models involving epileptic animals are useful to study whether epileptogen
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