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Titlebook: Antiepileptic Drug Discovery; Novel Approaches Alan Talevi,Luisa Rocha Book 2016 Springer Science+Business Media New York 2016 Antiepilepto

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發(fā)表于 2025-3-21 18:44:08 | 只看該作者 |倒序瀏覽 |閱讀模式
期刊全稱Antiepileptic Drug Discovery
期刊簡稱Novel Approaches
影響因子2023Alan Talevi,Luisa Rocha
視頻videohttp://file.papertrans.cn/159/158539/158539.mp4
發(fā)行地址Explores novel approaches for the development of antiepileptic therapies to combat pharmacoresistance.Features practical guidance for the implementation of important protocols.Serves as an ideal sourc
學科分類Methods in Pharmacology and Toxicology
圖書封面Titlebook: Antiepileptic Drug Discovery; Novel Approaches Alan Talevi,Luisa Rocha Book 2016 Springer Science+Business Media New York 2016 Antiepilepto
影響因子This thorough volume delves into antiepileptic drug discovery with a comprehensive collection of innovative approaches for the development of antiepileptic therapies, focusing on novel molecular targets for antiepileptic drugs, computer-aided approaches for the identification of new drug candidates, and therapeutic strategies to overcome refractory epilepsy. The last section illustrates the potential benefits that network pharmacology and rational drug repurposing could bring to the antiepileptic drug discovery community. Written for the .Methods in Pharmacology and Toxicology. series, chapters include the kind of detailed description and implementation advice to ensure results in the laboratory.?.Authoritative and practical, .Antiepileptic Drug Discovery: Novel Approaches. aims to provide medicinal chemists, pharmacologists, and other researchers with the tools need to further explore the study of pharmacoresistant epilepsy and the discovery of new antiepileptic drugs..
Pindex Book 2016
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Antiepileptic Drug Discovery978-1-4939-6355-3Series ISSN 1557-2153 Series E-ISSN 1940-6053
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發(fā)表于 2025-3-22 07:04:31 | 只看該作者
Angaben aus der Festigkeitslehre,the susceptibility to epileptic activity. Therefore, the search of pharmacological strategies focused on decreasing both neuroinflammation and neuronal excitability associated with epilepsy is important. This chapter is a review of several drugs that may be used for this purpose.
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Methods in Pharmacology and Toxicologyhttp://image.papertrans.cn/a/image/158539.jpg
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,Beziehung zwischen H?rte und Zugfestigkeit,d after seizures in experimental models and, in some cases, still overexpressed later during the chronic stage. Increased levels of these cytokines have been found in the serum from epileptic patients. Pharmacological approaches in rodents support that neuroinflammation is involved in modulating sei
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發(fā)表于 2025-3-23 00:02:43 | 只看該作者
Angaben aus der Festigkeitslehre,the susceptibility to epileptic activity. Therefore, the search of pharmacological strategies focused on decreasing both neuroinflammation and neuronal excitability associated with epilepsy is important. This chapter is a review of several drugs that may be used for this purpose.
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發(fā)表于 2025-3-23 04:33:16 | 只看該作者
Angaben aus der Festigkeitslehre,rly, the design of AEDs based on molecular targets constitutes a promising alternative to empirical screening, the traditional method to detect anticonvulsant action in new structures. In this chapter we described the advances in the dynamic field of carbonic anhydrases, with emphasis in the develop
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發(fā)表于 2025-3-23 08:37:20 | 只看該作者
Angaben aus der Festigkeitslehre,xpressed ubiquitously throughout the brain in all nerve terminals independently of their neurotransmitter. It plays an important role in ensuring correct neurotransmission by priming vesicles for fusion. SV2A is the molecular target of the anticonvulsant drug levetiracetam (LEV), whose effects might
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